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Inhibition by Sphingosine of Leukemic Cell Killing by Human Monocytes Activated with Interleukin‐2: A Possible Role of Protein Kinase C
Sphingosine and its analogs, which inhibit protein kinase C (PKC), are known to be potent inducers of apoptosis in tumor cells. However, we were concerned that sphingosine might also interfere with anti‐tumor cells of the immune system. Therefore, we evaluated the effect of sphingosine on activation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921842/ https://www.ncbi.nlm.nih.gov/pubmed/9685859 http://dx.doi.org/10.1111/j.1349-7006.1998.tb03296.x |