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Human Tumor Growth Suppression by Apoptosis Induced with Anti‐ErbB‐2 Chimeric Monoclonal Antibody

We established an anti‐ErbB‐2 mouse‐human chimeric monoclonal antibody (MoAb), CH401, which was able to kill cancer cells overexpressing the ErbB‐2 protein in vitro. The analysis of the killing mechanism indicated that MoAb CH401 might be the first anti‐ErbB‐2 mouse‐human chimeric MoAb which can ind...

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Detalles Bibliográficos
Autores principales:	Sasaki, Shigeru, Tsujisaki, Masayuki, Jinnohara, Tsuneharu, Ishida, Tadao, Sekiya, Masuo, Adachi, Masaaki, Takahashi, Shuji, Hinoda, Yuji, Imai, Kohzoh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921853/ https://www.ncbi.nlm.nih.gov/pubmed/9685861 http://dx.doi.org/10.1111/j.1349-7006.1998.tb03298.x

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