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Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors
The process of organ development requires a delicate balance between cellular plasticity and differentiation. This balance is disrupted in cancer initiation and progression. N-Myc and STAT interactor (NMI: human or Nmi: murine) has emerged as a relevant player in the etiology of breast cancer. Howev...
Autores principales: | Pruitt, Hawley C., Metge, Brandon J., Weeks, Shannon E., Chen, Dongquan, Wei, Shi, Kesterson, Robert A., Shevde, Lalita A., Samant, Rajeev S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921859/ https://www.ncbi.nlm.nih.gov/pubmed/29326438 http://dx.doi.org/10.1038/s41388-017-0037-7 |
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