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Development of High‐grade Renal Cell Carcinomas in Rats Independently of Somatic Mutations in the Tsc2 and VHL Tumor Suppressor Genes

Ferric nitrilotriacetate (Fe‐NTA) induces renal proximal tubular damage that ultimately leads to a high incidence of renal cell carcinoma (RCC) in rats. The RCCs are characterized by 1) high incidence of pulmonary metastasis and peritoneal invasion, 2) high incidence of tumor‐associated mortality an...

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Detalles Bibliográficos
Autores principales:	Toyokuni, Shinya, Okada, Kunihiko, Kondo, Shohei, Nishioka, Hiroaki, Tanaka, Tomoyuki, Nishiyama, Yasuyuki, Hino, Okio, Hiai, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921911/ https://www.ncbi.nlm.nih.gov/pubmed/9765616 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00633.x

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