Glucose‐Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid

Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide‐co‐poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis‐diol groups of glucose enables revers...

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Detalles Bibliográficos
Autores principales: Yetisen, Ali K., Jiang, Nan, Fallahi, Afsoon, Montelongo, Yunuen, Ruiz‐Esparza, Guillermo U., Tamayol, Ali, Zhang, Yu Shrike, Mahmood, Iram, Yang, Su‐A, Kim, Ki Su, Butt, Haider, Khademhosseini, Ali, Yun, Seok‐Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921932/
https://www.ncbi.nlm.nih.gov/pubmed/28195436
http://dx.doi.org/10.1002/adma.201606380
Descripción
Sumario:Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide‐co‐poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis‐diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for quantitative glucose measurements within the physiological range. [Image: see text]

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