Preferential Binding of E7010 to Murine β3‐Tubulin and Decreased β3‐Tubulin in E7010‐resistant Cell Lines

N‐[2‐[(4‐Hydroxyphenyl)amino]‐3‐pyridyl]‐4‐methoxybenzenesulfonamide (E7010) is a novel sulfonamide antimitotic agent, which is active against mouse and human tumors. E7010 binds to β‐tubulin and inhibits polymerization of microtubules. In order to clarify the mechanisms of E7010‐resistance, two mur...

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Detalles Bibliográficos
Autores principales: Iwamoto, Yasuo, Nishio, Kazuto, Fukumoto, Hisao, Yoshimatsu, Kentaro, Yamakido, Michio, Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921945/
https://www.ncbi.nlm.nih.gov/pubmed/9818032
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00654.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921945/
https://www.ncbi.nlm.nih.gov/pubmed/9818032
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00654.x

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