Induction of Apoptosis in Human Pancreatic Carcinoma Cells by a Synthetic Bleomycin‐like Ligand

Histidine‐pyridine‐histidine‐3 (HPH‐3) is an oxygen‐activating ligand based on the structure of bleomycin. HPH‐3 induced the death of human pancreatic adenocarcinoma AsPC‐1 cells in 24 h, causing apoptotic morphology and internucleosomal degradation of DNA. HPH‐3‐induced cell death was not inhibited...

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Detalles Bibliográficos
Autores principales: Suginaka, Rei, Izui, Reiko, Inoue, Jun‐ichiro, Muraoka, Yasuhiko, Yamaguchi, Ken, Otsuka, Masami, Umezawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921946/
https://www.ncbi.nlm.nih.gov/pubmed/9818031
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00653.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921946/
https://www.ncbi.nlm.nih.gov/pubmed/9818031
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00653.x

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