Genetic deletion of muscle RANK or selective inhibition of RANKL is not as effective as full-length OPG-fc in mitigating muscular dystrophy

Although there is a strong association between osteoporosis and skeletal muscle atrophy/dysfunction, the functional relevance of a particular biological pathway that regulates synchronously bone and skeletal muscle physiopathology is still elusive. Receptor-activator of nuclear factor κB (RANK), its...

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Detalles Bibliográficos
Autores principales: Dufresne, Sébastien S., Boulanger-Piette, Antoine, Bossé, Sabrina, Argaw, Anteneh, Hamoudi, Dounia, Marcadet, Laetitia, Gamu, Daniel, Fajardo, Val A., Yagita, Hideo, Penninger, Josef M., Russell Tupling, A., Frenette, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922009/
https://www.ncbi.nlm.nih.gov/pubmed/29699580
http://dx.doi.org/10.1186/s40478-018-0533-1

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