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Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter
BACKGROUND: The calcium-binding protein calretinin (gene name: CALB2) is currently considered as the most sensitive and specific marker for the diagnosis of malignant mesothelioma (MM). MM is a very aggressive tumor strongly linked to asbestos exposure and with no existing cure so far. The mechanism...
Autores principales: | Blum, Walter, Pecze, László, Rodriguez, Janine Wörthmüller, Steinauer, Martine, Schwaller, Beat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922012/ https://www.ncbi.nlm.nih.gov/pubmed/29699512 http://dx.doi.org/10.1186/s12885-018-4385-7 |
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