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rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling

Background: Pulmonary hypertension (PH) is a progressive cardiovascular disease, characterized by endothelial and smooth muscle dysfunction and vascular remodeling, followed by right heart failure. Group III PH develops secondarily to chronic lung disease such as idiopathic pulmonary fibrosis (IPF),...

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Detalles Bibliográficos
Autores principales: Rathinasabapathy, Anandharajan, Bryant, Andrew J., Suzuki, Toshio, Moore, Christy, Shay, Sheila, Gladson, Santhi, West, James D., Carrier, Erica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922219/
https://www.ncbi.nlm.nih.gov/pubmed/29731719
http://dx.doi.org/10.3389/fphys.2018.00271