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Peripheral tissues reprogram CD8(+) T cells for pathogenicity during graft-versus-host disease

Graft-versus-host disease (GVHD) is a life-threatening complication of allogeneic stem cell transplantation induced by the influx of donor-derived effector T cells (T(E)) into peripheral tissues. Current treatment strategies rely on targeting systemic T cells; however, the precise location and natur...

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Detalles Bibliográficos
Autores principales:	Santos e Sousa, Pedro, Ciré, Séverine, Conlan, Thomas, Jardine, Laura, Tkacz, Claire, Ferrer, Ivana R., Lomas, Cara, Ward, Sophie, West, Heather, Dertschnig, Simone, Blobner, Sven, Means, Terry K., Henderson, Stephen, Kaplan, Daniel H., Collin, Matthew, Plagnol, Vincent, Bennett, Clare L., Chakraverty, Ronjon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922296/ https://www.ncbi.nlm.nih.gov/pubmed/29515032 http://dx.doi.org/10.1172/jci.insight.97011

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