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MutationalPatterns: comprehensive genome-wide analysis of mutational processes

BACKGROUND: Base substitution catalogues represent historical records of mutational processes that have been active in a cell. Such processes can be distinguished by various characteristics, like mutation type, sequence context, transcriptional and replicative strand bias, genomic distribution and a...

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Detalles Bibliográficos
Autores principales: Blokzijl, Francis, Janssen, Roel, van Boxtel, Ruben, Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922316/
https://www.ncbi.nlm.nih.gov/pubmed/29695279
http://dx.doi.org/10.1186/s13073-018-0539-0