Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFR(mut) NSCLC in diagnosis, follow-up and treatment

Brain and leptomeningeal metastasis (LMM) of non-small cell lung cancer is still associated with poor prognosis. Moreover, the current diagnostic standard for LMM often yields false negative results and the scientific progress in this field is still unsatisfying. We present a case of a 71-year old p...

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Detalles Bibliográficos
Autores principales: Lüke, Florian, Blazquez, Raquel, Yamaci, Rezan Fahrioglu, Lu, Xin, Pregler, Benedikt, Hannus, Stefan, Menhart, Karin, Hellwig, Dirk, Wester, Hans-Jürgen, Kropf, Saskia, Heudobler, Daniel, Grosse, Jirka, Moosbauer, Jutta, Hutterer, Markus, Hau, Peter, Riemenschneider, Markus J., Bayerlová, Michaela, Bleckmann, Annalen, Polzer, Bernhard, Beißbarth, Tim, Klein, Christoph A., Pukrop, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922360/
https://www.ncbi.nlm.nih.gov/pubmed/29721166
http://dx.doi.org/10.18632/oncotarget.24787

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