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A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer
Immune checkpoint inhibitors produce modest responses in metastatic breast cancer, however, combination approaches may improve responses. A single arm pilot study was designed to determine the overall response rate (ORR) of durvalumab and tremelimumab, and evaluate immunogenomic dynamics in metastat...
Autores principales: | Santa-Maria, Cesar August, Kato, Taigo, Park, Jae-Hyun, Kiyotani, Kazuma, Rademaker, Alfred, Shah, Ami N., Gross, Leeaht, Blanco, Luis Z., Jain, Sarika, Flaum, Lisa, Tellez, Claudia, Stein, Regina, Uthe, Regina, Gradishar, William J., Cristofanilli, Massimo, Nakamura, Yusuke, Giles, Francis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922371/ https://www.ncbi.nlm.nih.gov/pubmed/29721177 http://dx.doi.org/10.18632/oncotarget.24867 |
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