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Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

BACKGROUND: Glypican-1 (GPC1) is expressed in pancreatic ductal adenocarcinoma (PDAC) cells and adjacent stromal fibroblasts. Recently, GPC1 circulating exosomes (crExos) have been shown to be able to detect early stages of PDAC. In this study, we investigated the usefulness of crExos GPC1 as a biom...

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Detalles Bibliográficos
Autores principales:	Frampton, Adam E., Prado, Mireia Mato, López-Jiménez, Elena, Fajardo-Puerta, Ana Belen, Jawad, Zaynab A.R., Lawton, Phillip, Giovannetti, Elisa, Habib, Nagy A., Castellano, Leandro, Stebbing, Justin, Krell, Jonathan, Jiao, Long R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922373/ https://www.ncbi.nlm.nih.gov/pubmed/29721179 http://dx.doi.org/10.18632/oncotarget.24873

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