Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer

Heparanase, the sole heparan sulfate (HS) degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, metastasis, angiogenesis, and inflammation. Heparanase accomplishes this by degrading HS and thereby facilitating cell invasion and regulating the bioavailability...

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Detalles Bibliográficos
Autores principales: Katz, Amit, Barash, Uri, Boyango, Ilanit, Feld, Sari, Zohar, Yaniv, Hammond, Edward, Ilan, Neta, Kremer, Ran, Vlodavsky, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922397/
https://www.ncbi.nlm.nih.gov/pubmed/29721203
http://dx.doi.org/10.18632/oncotarget.25022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922397/
https://www.ncbi.nlm.nih.gov/pubmed/29721203
http://dx.doi.org/10.18632/oncotarget.25022

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