Association of baseline absolute neutrophil counts and survival in patients with metastatic colorectal cancer treated with second-line antiangiogenic therapies: exploratory analyses of the RAISE trial and validation in an electronic medical record data set

BACKGROUND: In the RAISE trial, ramucirumab+leucovorin/fluorouracil/irinotecan (FOLFIRI) improved the median overall survival (mOS) of patients with previously treated metastatic colorectal cancer versus patients treated with placebo+FOLFIRI but had a higher incidence of neutropaenia, leading to mor...

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Detalles Bibliográficos
Autores principales: Grothey, Axel, Yoshino, Takayuki, Bodoky, Gyorgy, Ciuleanu, Tudor, Garcia-Carbonero, Rocio, García-Alfonso, Pilar, Van Cutsem, Eric, Muro, Kei, Mytelka, Daniel S, Li, Li, Lipkovich, Olga, Hsu, Yanzhi, Sashegyi, Andreas, Ferry, David, Nasroulah, Federico, Tabernero, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922565/
https://www.ncbi.nlm.nih.gov/pubmed/29713498
http://dx.doi.org/10.1136/esmoopen-2018-000347

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