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SHP2 inhibitor PHPS1 protects against atherosclerosis by inhibiting smooth muscle cell proliferation

BACKGROUND: Smooth muscle cells play an important role in the development of atherosclerosis. SHP2 is known to regulate the proliferation and migration of smooth muscle cells. The purpose of this study was to determine whether the SHP2 inhibitor PHPS1 has a pro-atherosclerotic or an atheroprotective...

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Detalles Bibliográficos
Autores principales:	Chen, Jia, Cao, Zhiyong, Guan, Jingshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923012/ https://www.ncbi.nlm.nih.gov/pubmed/29703160 http://dx.doi.org/10.1186/s12872-018-0816-2

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