Camelid Single-Domain Antibodies (VHHs) against Crotoxin: A Basis for Developing Modular Building Blocks for the Enhancement of Treatment or Diagnosis of Crotalic Envenoming

Toxic effects triggered by crotalic envenoming are mainly related to crotoxin (CTX), composed of a phospholipase A(2) (CB) and a subunit with no toxic activity (CA). Camelids produce immunoglobulins G devoid of light chains, in which the antigen recognition domain is called VHH. Given their unique c...

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Detalles Bibliográficos
Autores principales: Luiz, Marcos B., Pereira, Soraya S., Prado, Nidiane D. R., Gonçalves, Naan R., Kayano, Anderson M., Moreira-Dill, Leandro S., Sobrinho, Juliana C., Zanchi, Fernando B., Fuly, André L., Fernandes, Cleberson F., Zuliani, Juliana P., Soares, Andreimar M., Stabeli, Rodrigo G., Fernandes, Carla F. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923308/
https://www.ncbi.nlm.nih.gov/pubmed/29596324
http://dx.doi.org/10.3390/toxins10040142

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