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Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer

Background: Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such tumorigenesis are largely unknown. We have prev...

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Detalles Bibliográficos
Autores principales:	Manegold, Philipp, Lai, Keane K. Y., Wu, Yongfeng, Teo, Jia-Ling, Lenz, Heinz-Josef, Genyk, Yuri S., Pandol, Stephen J., Wu, Kaijin, Lin, David P., Chen, Yibu, Nguyen, Cu, Zhao, Yi, Kahn, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923350/ https://www.ncbi.nlm.nih.gov/pubmed/29596326 http://dx.doi.org/10.3390/cancers10040095

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