The Critical Role of Inflammation in the Pathogenesis and Progression of Myeloid Malignancies

Hematopoietic stem cells (HSCs) maintain an organism’s immune system for a lifetime, and derangements in HSC proliferation and differentiation result in hematologic malignancies. Chronic inflammation plays a contributory if not causal role in HSC dysfunction. Inflammation induces HSC exhaustion, whi...

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Detalles Bibliográficos
Autores principales: Craver, Brianna M., El Alaoui, Kenza, Scherber, Robyn M., Fleischman, Angela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923359/
https://www.ncbi.nlm.nih.gov/pubmed/29614027
http://dx.doi.org/10.3390/cancers10040104

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