YAP/TAZ Activation as a Target for Treating Metastatic Cancer

Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ) have both emerged as important drivers of cancer progression and metastasis. YAP and TAZ are often upregulated or nuclear localized in aggressive human cancers. There is abundant experimental evidence demonstr...

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Detalles Bibliográficos
Autores principales: Warren, Janine S. A., Xiao, Yuxuan, Lamar, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923370/
https://www.ncbi.nlm.nih.gov/pubmed/29642615
http://dx.doi.org/10.3390/cancers10040115

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