Cargando…

Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis

Mesenchymal stem cells (MSCs) are a source for cell-based therapy. Although MSCs have the potential for tissue regeneration, their therapeutic efficacy is restricted by the uremic toxin, p-cresol, in chronic kidney disease (CKD). To address this issue, we investigated the effect of fucoidan, a marin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jun Hee, Yun, Chul Won, Hur, Jin, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923408/
https://www.ncbi.nlm.nih.gov/pubmed/29642406
http://dx.doi.org/10.3390/md16040121