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Interaction of the Mouse Polyomavirus Capsid Proteins with Importins Is Required for Efficient Import of Viral DNA into the Cell Nucleus

The mechanism used by mouse polyomavirus (MPyV) to overcome the crowded cytosol to reach the nucleus has not been fully elucidated. Here, we investigated the involvement of importin α/β1 mediated transport in the delivery of MPyV genomes into the nucleus. Interactions of the virus with importin β1 w...

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Detalles Bibliográficos
Autores principales: Soldatova, Irina, Prilepskaja, Terezie, Abrahamyan, Levon, Forstová, Jitka, Huérfano, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923459/
https://www.ncbi.nlm.nih.gov/pubmed/29614718
http://dx.doi.org/10.3390/v10040165