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Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo

Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential f...

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Autores principales: Kakabadze, Elene, Makalatia, Khatuna, Grdzelishvili, Nino, Bakuradze, Nata, Goderdzishvili, Marina, Kusradze, Ia, Phoba, Marie-France, Lunguya, Octavie, Lood, Cédric, Lavigne, Rob, Jacobs, Jan, Deborggraeve, Stijn, De Block, Tessa, Van Puyvelde, Sandra, Lee, David, Coffey, Aidan, Sedrakyan, Anahit, Soentjens, Patrick, De Vos, Daniel, Pirnay, Jean-Paul, Chanishvili, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923466/
https://www.ncbi.nlm.nih.gov/pubmed/29614013
http://dx.doi.org/10.3390/v10040172
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author Kakabadze, Elene
Makalatia, Khatuna
Grdzelishvili, Nino
Bakuradze, Nata
Goderdzishvili, Marina
Kusradze, Ia
Phoba, Marie-France
Lunguya, Octavie
Lood, Cédric
Lavigne, Rob
Jacobs, Jan
Deborggraeve, Stijn
De Block, Tessa
Van Puyvelde, Sandra
Lee, David
Coffey, Aidan
Sedrakyan, Anahit
Soentjens, Patrick
De Vos, Daniel
Pirnay, Jean-Paul
Chanishvili, Nina
author_facet Kakabadze, Elene
Makalatia, Khatuna
Grdzelishvili, Nino
Bakuradze, Nata
Goderdzishvili, Marina
Kusradze, Ia
Phoba, Marie-France
Lunguya, Octavie
Lood, Cédric
Lavigne, Rob
Jacobs, Jan
Deborggraeve, Stijn
De Block, Tessa
Van Puyvelde, Sandra
Lee, David
Coffey, Aidan
Sedrakyan, Anahit
Soentjens, Patrick
De Vos, Daniel
Pirnay, Jean-Paul
Chanishvili, Nina
author_sort Kakabadze, Elene
collection PubMed
description Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general.
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spelling pubmed-59234662018-05-03 Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo Kakabadze, Elene Makalatia, Khatuna Grdzelishvili, Nino Bakuradze, Nata Goderdzishvili, Marina Kusradze, Ia Phoba, Marie-France Lunguya, Octavie Lood, Cédric Lavigne, Rob Jacobs, Jan Deborggraeve, Stijn De Block, Tessa Van Puyvelde, Sandra Lee, David Coffey, Aidan Sedrakyan, Anahit Soentjens, Patrick De Vos, Daniel Pirnay, Jean-Paul Chanishvili, Nina Viruses Brief Report Recently, a Salmonella Typhi isolate producing CTX-M-15 extended spectrum β-lactamase (ESBL) and with decreased ciprofloxacin susceptibility was isolated in the Democratic Republic of the Congo. We have selected bacteriophages that show strong lytic activity against this isolate and have potential for phage-based treatment of S. Typhi, and Salmonella in general. MDPI 2018-04-03 /pmc/articles/PMC5923466/ /pubmed/29614013 http://dx.doi.org/10.3390/v10040172 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Kakabadze, Elene
Makalatia, Khatuna
Grdzelishvili, Nino
Bakuradze, Nata
Goderdzishvili, Marina
Kusradze, Ia
Phoba, Marie-France
Lunguya, Octavie
Lood, Cédric
Lavigne, Rob
Jacobs, Jan
Deborggraeve, Stijn
De Block, Tessa
Van Puyvelde, Sandra
Lee, David
Coffey, Aidan
Sedrakyan, Anahit
Soentjens, Patrick
De Vos, Daniel
Pirnay, Jean-Paul
Chanishvili, Nina
Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title_full Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title_fullStr Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title_full_unstemmed Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title_short Selection of Potential Therapeutic Bacteriophages that Lyse a CTX-M-15 Extended Spectrum β-Lactamase Producing Salmonella enterica Serovar Typhi Strain from the Democratic Republic of the Congo
title_sort selection of potential therapeutic bacteriophages that lyse a ctx-m-15 extended spectrum β-lactamase producing salmonella enterica serovar typhi strain from the democratic republic of the congo
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923466/
https://www.ncbi.nlm.nih.gov/pubmed/29614013
http://dx.doi.org/10.3390/v10040172
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