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Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults

Humans are exposed to the environmental pollutants 2,4-dichlorophenol (2,4-DCP) and 2,5-dichlorophenol (2,5-DCP) through air, the use of water and the consumption of products. In this study, we evaluated the urinary concentrations of these compounds in Korean people between the ages of 18 to 69 year...

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Autores principales: Park, Hyejin, Kim, Kisok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923631/
https://www.ncbi.nlm.nih.gov/pubmed/29587398
http://dx.doi.org/10.3390/ijerph15040589
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author Park, Hyejin
Kim, Kisok
author_facet Park, Hyejin
Kim, Kisok
author_sort Park, Hyejin
collection PubMed
description Humans are exposed to the environmental pollutants 2,4-dichlorophenol (2,4-DCP) and 2,5-dichlorophenol (2,5-DCP) through air, the use of water and the consumption of products. In this study, we evaluated the urinary concentrations of these compounds in Korean people between the ages of 18 to 69 years, by making use of data from the Korean National Human Biomonitoring Survey that was completed in 2009. Of 1865 representative Koreans, 63.4% and 97.9% were found to have concentrations of 2,4-DCP and 2,5-DCP > 0.05 μg/L (limit of detection) in their urine, respectively. The geometric mean of urinary concentrations was 0.14 μg/L (confidence interval of 95% = 0.13–0.16) and 0.44 μg/L (confidence interval = 0.41–0.48), respectively. It was found that the adjusted proportional changes in 2,4-DCP concentrations were significantly associated with body mass index, whereas those of 2,5-DCP concentrations were influenced by place of residence. From these findings, it is evident that most adults in Korea have levels of 2,4-DCP and 2,5-DCP that are detectable in their urine and the burden of these compounds on their bodies varies depending on numerous demographic factors.
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spelling pubmed-59236312018-05-03 Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults Park, Hyejin Kim, Kisok Int J Environ Res Public Health Article Humans are exposed to the environmental pollutants 2,4-dichlorophenol (2,4-DCP) and 2,5-dichlorophenol (2,5-DCP) through air, the use of water and the consumption of products. In this study, we evaluated the urinary concentrations of these compounds in Korean people between the ages of 18 to 69 years, by making use of data from the Korean National Human Biomonitoring Survey that was completed in 2009. Of 1865 representative Koreans, 63.4% and 97.9% were found to have concentrations of 2,4-DCP and 2,5-DCP > 0.05 μg/L (limit of detection) in their urine, respectively. The geometric mean of urinary concentrations was 0.14 μg/L (confidence interval of 95% = 0.13–0.16) and 0.44 μg/L (confidence interval = 0.41–0.48), respectively. It was found that the adjusted proportional changes in 2,4-DCP concentrations were significantly associated with body mass index, whereas those of 2,5-DCP concentrations were influenced by place of residence. From these findings, it is evident that most adults in Korea have levels of 2,4-DCP and 2,5-DCP that are detectable in their urine and the burden of these compounds on their bodies varies depending on numerous demographic factors. MDPI 2018-03-25 2018-04 /pmc/articles/PMC5923631/ /pubmed/29587398 http://dx.doi.org/10.3390/ijerph15040589 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Hyejin
Kim, Kisok
Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title_full Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title_fullStr Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title_full_unstemmed Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title_short Concentrations of 2,4-Dichlorophenol and 2,5-Dichlorophenol in Urine of Korean Adults
title_sort concentrations of 2,4-dichlorophenol and 2,5-dichlorophenol in urine of korean adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923631/
https://www.ncbi.nlm.nih.gov/pubmed/29587398
http://dx.doi.org/10.3390/ijerph15040589
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