Cargando…

Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products

The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the conce...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Minjin, Kim, Joo-Hyon, Lee, Daeyeop, Kim, Jaewoo, Lim, Hyunwoo, Seo, Jungkwan, Park, Young-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923786/
https://www.ncbi.nlm.nih.gov/pubmed/29652814
http://dx.doi.org/10.3390/ijerph15040744
_version_ 1783318423964483584
author Lee, Minjin
Kim, Joo-Hyon
Lee, Daeyeop
Kim, Jaewoo
Lim, Hyunwoo
Seo, Jungkwan
Park, Young-Kwon
author_facet Lee, Minjin
Kim, Joo-Hyon
Lee, Daeyeop
Kim, Jaewoo
Lim, Hyunwoo
Seo, Jungkwan
Park, Young-Kwon
author_sort Lee, Minjin
collection PubMed
description The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. The risk assessment study followed a stepwise procedure (e.g., collecting toxicological information, hazard identification/exposure assessment, and screening and detailed assessment for inhalation and dermal routes). The worst-case scenario and maximum concentration determined by the product purpose and application type were used as the screening assessment. In a detailed assessment, the 75th exposure factor values were used to estimate the assumed reasonable exposure to ingredients. The exposed concentrations of seven ingredients were calculated. Due to limitation of toxicity information, butylated hydroxyl toluene for a consumer’s exposure via the dermal route only was conducted for a detailed assessment. This study showed that the assessed ingredients have no health risks at their maximum concentrations in deodorizing products. This approach can be used to establish guidelines for ingredients that may pose inhalation and dermal hazards.
format Online
Article
Text
id pubmed-5923786
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-59237862018-05-03 Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products Lee, Minjin Kim, Joo-Hyon Lee, Daeyeop Kim, Jaewoo Lim, Hyunwoo Seo, Jungkwan Park, Young-Kwon Int J Environ Res Public Health Article The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. The risk assessment study followed a stepwise procedure (e.g., collecting toxicological information, hazard identification/exposure assessment, and screening and detailed assessment for inhalation and dermal routes). The worst-case scenario and maximum concentration determined by the product purpose and application type were used as the screening assessment. In a detailed assessment, the 75th exposure factor values were used to estimate the assumed reasonable exposure to ingredients. The exposed concentrations of seven ingredients were calculated. Due to limitation of toxicity information, butylated hydroxyl toluene for a consumer’s exposure via the dermal route only was conducted for a detailed assessment. This study showed that the assessed ingredients have no health risks at their maximum concentrations in deodorizing products. This approach can be used to establish guidelines for ingredients that may pose inhalation and dermal hazards. MDPI 2018-04-13 2018-04 /pmc/articles/PMC5923786/ /pubmed/29652814 http://dx.doi.org/10.3390/ijerph15040744 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Minjin
Kim, Joo-Hyon
Lee, Daeyeop
Kim, Jaewoo
Lim, Hyunwoo
Seo, Jungkwan
Park, Young-Kwon
Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title_full Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title_fullStr Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title_full_unstemmed Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title_short Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products
title_sort health risk assessment on hazardous ingredients in household deodorizing products
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923786/
https://www.ncbi.nlm.nih.gov/pubmed/29652814
http://dx.doi.org/10.3390/ijerph15040744
work_keys_str_mv AT leeminjin healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT kimjoohyon healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT leedaeyeop healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT kimjaewoo healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT limhyunwoo healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT seojungkwan healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts
AT parkyoungkwon healthriskassessmentonhazardousingredientsinhouseholddeodorizingproducts