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Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography

Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which w...

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Autores principales: Mahajan, Abhimanyu, Zillgitt, Andrew, Bowyer, Susan M., Sidiropoulos, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924387/
https://www.ncbi.nlm.nih.gov/pubmed/29565281
http://dx.doi.org/10.3390/brainsci8040051
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author Mahajan, Abhimanyu
Zillgitt, Andrew
Bowyer, Susan M.
Sidiropoulos, Christos
author_facet Mahajan, Abhimanyu
Zillgitt, Andrew
Bowyer, Susan M.
Sidiropoulos, Christos
author_sort Mahajan, Abhimanyu
collection PubMed
description Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which was described as yawning. Study revealed connectivity between the left frontal and inferior frontal gyrus before yawning, which changed to the visual cortex and right middle frontal gyrus with yawning. Beta frequencies reduced and gamma frequencies increased after yawning. Discussion: The increase in gamma frequency bands may indicate increased GABAergic activity. Increase in connectivity in the right cerebellar region underscores the importance of cerebellum in pathogenesis of dystonia.
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spelling pubmed-59243872018-05-03 Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography Mahajan, Abhimanyu Zillgitt, Andrew Bowyer, Susan M. Sidiropoulos, Christos Brain Sci Case Report Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which was described as yawning. Study revealed connectivity between the left frontal and inferior frontal gyrus before yawning, which changed to the visual cortex and right middle frontal gyrus with yawning. Beta frequencies reduced and gamma frequencies increased after yawning. Discussion: The increase in gamma frequency bands may indicate increased GABAergic activity. Increase in connectivity in the right cerebellar region underscores the importance of cerebellum in pathogenesis of dystonia. MDPI 2018-03-22 /pmc/articles/PMC5924387/ /pubmed/29565281 http://dx.doi.org/10.3390/brainsci8040051 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Mahajan, Abhimanyu
Zillgitt, Andrew
Bowyer, Susan M.
Sidiropoulos, Christos
Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title_full Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title_fullStr Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title_full_unstemmed Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title_short Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
title_sort sensory trick in a patient with cervical dystonia: insights from magnetoencephalography
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924387/
https://www.ncbi.nlm.nih.gov/pubmed/29565281
http://dx.doi.org/10.3390/brainsci8040051
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