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Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography
Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924387/ https://www.ncbi.nlm.nih.gov/pubmed/29565281 http://dx.doi.org/10.3390/brainsci8040051 |
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author | Mahajan, Abhimanyu Zillgitt, Andrew Bowyer, Susan M. Sidiropoulos, Christos |
author_facet | Mahajan, Abhimanyu Zillgitt, Andrew Bowyer, Susan M. Sidiropoulos, Christos |
author_sort | Mahajan, Abhimanyu |
collection | PubMed |
description | Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which was described as yawning. Study revealed connectivity between the left frontal and inferior frontal gyrus before yawning, which changed to the visual cortex and right middle frontal gyrus with yawning. Beta frequencies reduced and gamma frequencies increased after yawning. Discussion: The increase in gamma frequency bands may indicate increased GABAergic activity. Increase in connectivity in the right cerebellar region underscores the importance of cerebellum in pathogenesis of dystonia. |
format | Online Article Text |
id | pubmed-5924387 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-59243872018-05-03 Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography Mahajan, Abhimanyu Zillgitt, Andrew Bowyer, Susan M. Sidiropoulos, Christos Brain Sci Case Report Background: The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement. Case report: A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which was described as yawning. Study revealed connectivity between the left frontal and inferior frontal gyrus before yawning, which changed to the visual cortex and right middle frontal gyrus with yawning. Beta frequencies reduced and gamma frequencies increased after yawning. Discussion: The increase in gamma frequency bands may indicate increased GABAergic activity. Increase in connectivity in the right cerebellar region underscores the importance of cerebellum in pathogenesis of dystonia. MDPI 2018-03-22 /pmc/articles/PMC5924387/ /pubmed/29565281 http://dx.doi.org/10.3390/brainsci8040051 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Mahajan, Abhimanyu Zillgitt, Andrew Bowyer, Susan M. Sidiropoulos, Christos Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title | Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title_full | Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title_fullStr | Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title_full_unstemmed | Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title_short | Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography |
title_sort | sensory trick in a patient with cervical dystonia: insights from magnetoencephalography |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924387/ https://www.ncbi.nlm.nih.gov/pubmed/29565281 http://dx.doi.org/10.3390/brainsci8040051 |
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