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Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
Integrins are a large family of adhesion molecules that mediate cell-cell and cell-extracellular matrix interactions. Among the 24 integrin isoforms, many have been found to be associated with tumor angiogenesis, tumor cell migration and proliferation, and metastasis. Integrins, especially αvβ3, αvβ...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924434/ https://www.ncbi.nlm.nih.gov/pubmed/29703238 http://dx.doi.org/10.1186/s13046-018-0763-x |