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Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study

OBJECTIVE: All childhood vaccines, except the oral polio vaccine, should be kept at 2–8 °C, since the vaccine potency can be damaged by heat or freezing temperature. A temperature monitoring study conducted in 2008–2009 reported challenges in cold chain management from the provincial level downwards...

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Autores principales: Kitamura, Tomomi, Bouakhasith, Viraneth, Phounphenghack, Kongxay, Pathammavong, Chansay, Xeuatvongsa, Anonh, Norizuki, Masataro, Okabayashi, Hironori, Mori, Yoshio, Machida, Munehito, Hachiya, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924473/
https://www.ncbi.nlm.nih.gov/pubmed/29703228
http://dx.doi.org/10.1186/s13104-018-3362-1
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author Kitamura, Tomomi
Bouakhasith, Viraneth
Phounphenghack, Kongxay
Pathammavong, Chansay
Xeuatvongsa, Anonh
Norizuki, Masataro
Okabayashi, Hironori
Mori, Yoshio
Machida, Munehito
Hachiya, Masahiko
author_facet Kitamura, Tomomi
Bouakhasith, Viraneth
Phounphenghack, Kongxay
Pathammavong, Chansay
Xeuatvongsa, Anonh
Norizuki, Masataro
Okabayashi, Hironori
Mori, Yoshio
Machida, Munehito
Hachiya, Masahiko
author_sort Kitamura, Tomomi
collection PubMed
description OBJECTIVE: All childhood vaccines, except the oral polio vaccine, should be kept at 2–8 °C, since the vaccine potency can be damaged by heat or freezing temperature. A temperature monitoring study conducted in 2008–2009 reported challenges in cold chain management from the provincial level downwards. The present cross-sectional pilot study aimed to assess the current status of the cold chain in two provinces (Saravan and Xayabouly) of Lao People’s Democratic Republic between March–April 2016. Two types of temperature data loggers recorded the temperatures and the proportions of time exposed to < 0 or > 8 °C were calculated. RESULTS: The temperature remained within the appropriate range in the central and provincial storages. However, the vaccines were frequently exposed to > 8 °C in Saravan and < 0 °C in Xayabouly in the district storage. Vaccines were exposed to > 8 °C during the transportation in Saravan and to both > 8 and < 0 °C in Xayabouly. Thus, challenges in managing the cold chain in the district storage and during transportation remain, despite improvements at the provincial storage. A detailed up-to-date nationwide analysis of the current situation of the cold chain is warranted to identify the most appropriate intervention to tackle the remaining challenges.
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spelling pubmed-59244732018-05-01 Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study Kitamura, Tomomi Bouakhasith, Viraneth Phounphenghack, Kongxay Pathammavong, Chansay Xeuatvongsa, Anonh Norizuki, Masataro Okabayashi, Hironori Mori, Yoshio Machida, Munehito Hachiya, Masahiko BMC Res Notes Research Note OBJECTIVE: All childhood vaccines, except the oral polio vaccine, should be kept at 2–8 °C, since the vaccine potency can be damaged by heat or freezing temperature. A temperature monitoring study conducted in 2008–2009 reported challenges in cold chain management from the provincial level downwards. The present cross-sectional pilot study aimed to assess the current status of the cold chain in two provinces (Saravan and Xayabouly) of Lao People’s Democratic Republic between March–April 2016. Two types of temperature data loggers recorded the temperatures and the proportions of time exposed to < 0 or > 8 °C were calculated. RESULTS: The temperature remained within the appropriate range in the central and provincial storages. However, the vaccines were frequently exposed to > 8 °C in Saravan and < 0 °C in Xayabouly in the district storage. Vaccines were exposed to > 8 °C during the transportation in Saravan and to both > 8 and < 0 °C in Xayabouly. Thus, challenges in managing the cold chain in the district storage and during transportation remain, despite improvements at the provincial storage. A detailed up-to-date nationwide analysis of the current situation of the cold chain is warranted to identify the most appropriate intervention to tackle the remaining challenges. BioMed Central 2018-04-27 /pmc/articles/PMC5924473/ /pubmed/29703228 http://dx.doi.org/10.1186/s13104-018-3362-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Kitamura, Tomomi
Bouakhasith, Viraneth
Phounphenghack, Kongxay
Pathammavong, Chansay
Xeuatvongsa, Anonh
Norizuki, Masataro
Okabayashi, Hironori
Mori, Yoshio
Machida, Munehito
Hachiya, Masahiko
Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title_full Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title_fullStr Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title_full_unstemmed Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title_short Assessment of temperatures in the vaccine cold chain in two provinces in Lao People’s Democratic Republic: a cross-sectional pilot study
title_sort assessment of temperatures in the vaccine cold chain in two provinces in lao people’s democratic republic: a cross-sectional pilot study
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924473/
https://www.ncbi.nlm.nih.gov/pubmed/29703228
http://dx.doi.org/10.1186/s13104-018-3362-1
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