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Development of a computational promoter with highly efficient expression in tumors

BACKGROUND: Gene therapy is a potent method to increase the therapeutic efficacy against cancer. However, a gene that is specifically expressed in the tumor area has not been identified. In addition, nonspecific expression of therapeutic genes in normal tissues may cause side effects that can harm t...

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Detalles Bibliográficos
Autores principales:	Ho, Shu-Yi, Chang, Bo-Hau, Chung, Chen-Han, Lin, Yu-Ling, Chuang, Cheng-Hsun, Hsieh, Pei-Jung, Huang, Wei-Chih, Tsai, Nu-Man, Huang, Sheng-Chieh, Liu, Yen-Ku, Lo, Yu-Chih, Liao, Kuang-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924487/ https://www.ncbi.nlm.nih.gov/pubmed/29703163 http://dx.doi.org/10.1186/s12885-018-4421-7

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