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Roles of Mitochondrial DNA Mutations in Stem Cell Ageing

Mitochondrial DNA (mtDNA) mutations accumulate in somatic stem cells during ageing and cause mitochondrial dysfunction. In this review, we summarize the studies that link mtDNA mutations to stem cell ageing. We discuss the age-related behaviours of the somatic mtDNA mutations in stem cell population...

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Detalles Bibliográficos
Autores principales:	Su, Tianhong, Turnbull, Doug M., Greaves, Laura C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924524/ https://www.ncbi.nlm.nih.gov/pubmed/29584704 http://dx.doi.org/10.3390/genes9040182

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