Cargando…

TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor

Metabolic reprogramming is an important issue in tumor biology. An unexpected inter- and intra-tumor metabolic heterogeneity has been strictly correlated to tumor outcome. Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP1) is a molecular chaperone involved in the regulation of energetic met...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matassa, Danilo Swann, Agliarulo, Ilenia, Avolio, Rosario, Landriscina, Matteo, Esposito, Franca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924537/ https://www.ncbi.nlm.nih.gov/pubmed/29621137 http://dx.doi.org/10.3390/genes9040195

Ejemplares similares

Regulation of mitochondrial complex III activity and assembly by TRAP1 in cancer cells
por: Matassa, Danilo Swann, et al.
Publicado: (2022)

TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transition
por: Amoroso, Maria R, et al.
Publicado: (2016)

Modulation of Mitochondrial Metabolic Reprogramming and Oxidative Stress to Overcome Chemoresistance in Cancer
por: Avolio, Rosario, et al.
Publicado: (2020)

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins
por: Avolio, Rosario, et al.
Publicado: (2023)

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins
por: Avolio, Rosario, et al.
Publicado: (2023)

Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation
por: Avolio, Rosario, et al.
Publicado: (2018)

HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy
por: Condelli, Valentina, et al.
Publicado: (2019)

Targeting Mitochondrial Protein Expression as a Future Approach for Cancer Therapy
por: Criscuolo, Daniela, et al.
Publicado: (2021)

TRAP1 regulates the response of colorectal cancer cells to hypoxia and inhibits ribosome biogenesis under conditions of oxygen deprivation
por: Bruno, Giuseppina, et al.
Publicado: (2022)

Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: A novel strategy for human BRAF-driven colorectal carcinoma
por: Condelli, Valentina, et al.
Publicado: (2015)

TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas
por: Maddalena, Francesca, et al.
Publicado: (2020)

Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer
por: Criscuolo, Daniela, et al.
Publicado: (2022)

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo
por: Pepe, Anna, et al.
Publicado: (2017)

Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer
por: Criscuolo, Daniela, et al.
Publicado: (2020)

Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
por: Matassa, D S, et al.
Publicado: (2013)

Oncogenes and Tumor Suppressors Regulate Glutamine Metabolism in Cancer Cells
por: Kim, Min Hyun, et al.
Publicado: (2013)

Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
por: Matassa, D S, et al.
Publicado: (2016)

TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma
por: Maddalena, Francesca, et al.
Publicado: (2017)

Golgi Apparatus Regulates Plasma Membrane Composition and Function
por: Agliarulo, Ilenia, et al.
Publicado: (2022)

TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation
por: Lettini, Giacomo, et al.
Publicado: (2020)

Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression
por: Crispo, Fabiana, et al.
Publicado: (2019)

Tumor-Suppressor Genes and Oncogenes
Publicado: (1993)

Oncogenes and tumor-suppressor genes.
por: Lehman, T A, et al.
Publicado: (1991)

CDK10 in Gastrointestinal Cancers: Dual Roles as a Tumor Suppressor and Oncogene
por: Bazzi, Zainab A., et al.
Publicado: (2021)

Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas
por: Pietrafesa, Michele, et al.
Publicado: (2019)

Dysregulation of Glucose Metabolism by Oncogenes and Tumor Suppressors in Cancer Cells
por: Marbaniang, Casterland, et al.
Publicado: (2018)

TRAP1 and SORCIN cooperate in a survival pathway responsible for inducing drug-resistance in human colorectal carcinoma (CRC)
por: Landriscina, Matteo, et al.
Publicado: (2010)

RUNX family: Oncogenes or tumor suppressors
por: Otálora-Otálora, Beatriz Andrea, et al.
Publicado: (2019)

Epigenetic regulation of ID4 in breast cancer: tumor suppressor or oncogene?
por: Nasif, Daniela, et al.
Publicado: (2018)

KRAB-ZFP Transcriptional Regulators Acting as Oncogenes and Tumor Suppressors: An Overview
por: Sobocińska, Joanna, et al.
Publicado: (2021)

Angiomotin Family Members: Oncogenes or Tumor Suppressors?
por: Lv, Meng, et al.
Publicado: (2017)

SIRT3: Oncogene and Tumor Suppressor in Cancer
por: Torrens-Mas, Margalida, et al.
Publicado: (2017)

The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
por: Sciacovelli, Marco, et al.
Publicado: (2013)

PTEN: Tumor Suppressor and Metabolic Regulator
por: Chen, Chien-Yu, et al.
Publicado: (2018)

Oncogenic regulation of tumor metabolic reprogramming
por: Tarrado-Castellarnau, Míriam, et al.
Publicado: (2016)

Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis.
por: Lechner, J F, et al.
Publicado: (1997)

Genetic Basis for Carcinogenesis. Tumor Suppressor Genes and Oncogenes
por: Rabbitts, P.
Publicado: (1992)

Is miR-29 an oncogene or tumor suppressor in CLL?
por: Pekarsky, Yuri, et al.
Publicado: (2010)

IGF-Binding Protein 2 – Oncogene or Tumor Suppressor?
por: Pickard, Adam, et al.
Publicado: (2015)

RhoB: Team Oncogene or Team Tumor Suppressor?
por: Ju, Julia A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d4i2hinjg69f7ecih33u8555ia