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The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth

Deubiquitinases (DUBs) play essential roles in normal cell proliferation and tumor growth. However, the molecular mechanisms of DUBs on hepatocellular carcinoma (HCC) remains largely unknown. In this study, based on analysis of several HCC datasets, we found that the USP21 gene, which encodes a memb...

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Detalles Bibliográficos
Autores principales: Li, Wenjuan, Cui, Kaisa, Prochownik, Edward V, Li, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924753/
https://www.ncbi.nlm.nih.gov/pubmed/29706623
http://dx.doi.org/10.1038/s41419-018-0523-z

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