Cargando…

ECD promotes gastric cancer metastasis by blocking E3 ligase ZFP91-mediated hnRNP F ubiquitination and degradation

The human ortholog of the Drosophila ecdysoneless gene (ECD) is required for embryonic development and cell-cycle progression; however, its role in cancer progression and metastasis remains unclear. Here, we found that ECD is frequently overexpressed in gastric cancer (GC), especially in metastatic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Song-Hui, Zhu, Song, Wang, Yanjie, Huang, Jin-Zhou, Chen, Min, Wu, Qing-Xia, He, Yu-Tian, Chen, De, Yan, Guang-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924763/ https://www.ncbi.nlm.nih.gov/pubmed/29706618 http://dx.doi.org/10.1038/s41419-018-0525-x

Ejemplares similares

Paralogs hnRNP L and hnRNP LL Exhibit Overlapping but Distinct RNA Binding Constraints
por: Smith, Sarah A., et al.
Publicado: (2013)

hnRNP Q and hnRNP A1 Regulate the Translation of Cofilin in Response to Transient Oxygen–Glucose Deprivation in Hippocampal Neurons
por: Kim, Sung Wook, et al.
Publicado: (2021)

hnRNP A1 and hnRNP F Modulate the Alternative Splicing of Exon 11 of the Insulin Receptor Gene
por: Talukdar, Indrani, et al.
Publicado: (2011)

HnRNP L represses cryptic exons
por: McClory, Sean P., et al.
Publicado: (2018)

HnRNP Pathologies in Frontotemporal Lobar Degeneration
por: Jiang, Xinwa, et al.
Publicado: (2023)

The Eµ-hnRNP K Murine Model of Lymphoma: Novel Insights into the Role of hnRNP K in B-Cell Malignancies
por: Malaney, Prerna, et al.
Publicado: (2021)

Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing
por: Martinez-Contreras, Rebeca, et al.
Publicado: (2006)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA
por: Rahman, Mohammad Alinoor, et al.
Publicado: (2013)

hnRNP A1 and hnRNP C associate with miR‐17 and miR‐18 in thyroid cancer cells
por: dos Santos, Maria Gabriela Pereira, et al.
Publicado: (2022)

The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
por: Howley, Breege V., et al.
Publicado: (2022)

Isolation of hnRNP complexes from Drosophila melanogaster
Publicado: (1992)

The hnRNP family: insights into their role in health and disease
por: Geuens, Thomas, et al.
Publicado: (2016)

Linking hnRNP Function to ALS and FTD Pathology
por: Purice, Maria D., et al.
Publicado: (2018)

An analysis of the role of HnRNP C dysregulation in cancers
por: Mo, Liyi, et al.
Publicado: (2022)

SDCBP‐AS1 destabilizes β‐catenin by regulating ubiquitination and SUMOylation of hnRNP K to suppress gastric tumorigenicity and metastasis
por: Han, Jing, et al.
Publicado: (2022)

Characterization of the major hnRNP proteins from Drosophila melanogaster
Publicado: (1992)

Caspase-3 cleaves hnRNP K in erythroid differentiation
por: Naarmann-de Vries, I S, et al.
Publicado: (2013)

Stress-Induced Accumulation of HnRNP K into Stress Granules
por: Kim, Jayoung, et al.
Publicado: (2021)

E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing
por: Chen, De, et al.
Publicado: (2020)

A nuclear localization domain in the hnRNP A1 protein
Publicado: (1995)

Association of individual hnRNP proteins and snRNPs with nascent transcripts
Publicado: (1993)

AUF1/hnRNP D represses expression of VEGF in macrophages
por: Fellows, Abigail, et al.
Publicado: (2012)

hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay
por: Reznik, Boris, et al.
Publicado: (2014)

hnRNP A1: The Swiss Army Knife of Gene Expression
por: Jean-Philippe, Jacques, et al.
Publicado: (2013)

Phosphorylation of hnRNP K controls cytosolic accumulation of TDP-43
por: White, Anthony, et al.
Publicado: (2013)

Identification and characterization of an hnRNP E1 translational silencing motif
por: Brown, Andrew S., et al.
Publicado: (2016)

Telomere Function and the G-Quadruplex Formation are Regulated by hnRNP U
por: Izumi, Hiroto, et al.
Publicado: (2019)

The Novel Role of hnRNP UL1 in Human Cell Nucleoli
por: Cichocka, Marlena, et al.
Publicado: (2022)

HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform
por: Nasrin, Farhana, et al.
Publicado: (2014)

High hnRNP AB expression is associated with poor prognosis in patients with colorectal cancer
por: Zhou, Jun-Min, et al.
Publicado: (2019)

HnRNP A1 is Involved in Deep Vein Thrombosis Patients with Behçet's Disease
por: Chen, Peng, et al.
Publicado: (2016)

HuR-Regulated mRNAs Associated with Nuclear hnRNP A1-RNP Complexes
por: Papadodima, Olga, et al.
Publicado: (2013)

Downregulation of hnRNP K by RNAi inhibits growth of human lung carcinoma cells
por: TANG, FENGMING, et al.
Publicado: (2014)

hnRNP-R regulates the PMA-induced c-fos expression in retinal cells
por: Huang, Jia, et al.
Publicado: (2008)

Distribution studies on polytene chromosomes using antibodies directed against hnRNP
Publicado: (1981)

Upregulation of UCP2 by Adiponectin: The Involvement of Mitochondrial Superoxide and hnRNP K
por: Zhou, Mingyan, et al.
Publicado: (2012)

TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres
por: Le, Phuong N., et al.
Publicado: (2013)

The hnRNP-Q Protein LIF2 Participates in the Plant Immune Response
por: Le Roux, Clémentine, et al.
Publicado: (2014)

hnRNP A1 and secondary structure coordinate alternative splicing of Mag
por: Zearfoss, N. Ruth, et al.
Publicado: (2013)

Regulation of tyrosine hydroxylase transcription by hnRNP K and DNA secondary structure
por: Banerjee, Kasturi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_plfa2b3pqpbss1fjq2ot19hgm7