Antigenicity of Leishmania-Activated C-Kinase Antigen (LACK) in Human Peripheral Blood Mononuclear Cells, and Protective Effect of Prime-Boost Vaccination With pCI-neo-LACK Plus Attenuated LACK-Expressing Vaccinia Viruses in Hamsters

Leishmania-activated C-kinase antigen (LACK) is a highly conserved protein among Leishmania species and is considered a viable vaccine candidate for human leishmaniasis. In animal models, prime-boost vaccination with LACK-expressing plasmids plus attenuated vaccinia viruses (modified vaccinia Ankara...

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Detalles Bibliográficos
Autores principales: Fernández, Laura, Carrillo, Eugenia, Sánchez-Sampedro, Lucas, Sánchez, Carmen, Ibarra-Meneses, Ana Victoria, Jimenez, Mͣ Angeles, Almeida, Valter dos Anjos, Esteban, Mariano, Moreno, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924775/
https://www.ncbi.nlm.nih.gov/pubmed/29740446
http://dx.doi.org/10.3389/fimmu.2018.00843

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