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Inhibition of Epac2 Attenuates Neural Cell Apoptosis and Improves Neurological Deficits in a Rat Model of Traumatic Brain Injury
Traumatic brain injury (TBI) is a major cause of mortality and disability worldwide. TBI-induced neuronal apoptosis is one of the main contributors to the secondary injury process. The aim of this study is to investigate the involvement of Exchange protein directly activated by cAMP 2 (Epac2) on TBI...
Autores principales: | Zhang, Ling, Zhang, Li, Liu, Huixiang, Jiang, Feng, Wang, Huanjing, Li, Di, Gao, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924794/ https://www.ncbi.nlm.nih.gov/pubmed/29740274 http://dx.doi.org/10.3389/fnins.2018.00263 |
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