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Biphasic voltage‐dependent inactivation of human Na(V)1.3, 1.6 and 1.7 Na(+) channels expressed in rodent insulin‐secreting cells
KEY POINTS: Na(+) current inactivation is biphasic in insulin‐secreting cells, proceeding with two voltage dependences that are half‐maximal at ∼−100 mV and −60 mV. Inactivation of voltage‐gated Na(+) (Na(V)) channels occurs at ∼30 mV more negative voltages in insulin‐secreting Ins1 and primary β‐ce...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924821/ https://www.ncbi.nlm.nih.gov/pubmed/29441586 http://dx.doi.org/10.1113/JP275587 |