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Glucagon contributes to liver zonation
Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate...
Autores principales: | Cheng, Xiping, Kim, Sun Y., Okamoto, Haruka, Xin, Yurong, Yancopoulos, George D., Murphy, Andrew J., Gromada, Jesper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924920/ https://www.ncbi.nlm.nih.gov/pubmed/29555772 http://dx.doi.org/10.1073/pnas.1721403115 |
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