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Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper

We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 mo...

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Detalles Bibliográficos
Autores principales: Singh, Anshul, Chaudhary, Ashu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925014/
https://www.ncbi.nlm.nih.gov/pubmed/29849539
http://dx.doi.org/10.1155/2018/2467463
Descripción
Sumario:We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats.