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Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 mo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925014/ https://www.ncbi.nlm.nih.gov/pubmed/29849539 http://dx.doi.org/10.1155/2018/2467463 |
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author | Singh, Anshul Chaudhary, Ashu |
author_facet | Singh, Anshul Chaudhary, Ashu |
author_sort | Singh, Anshul |
collection | PubMed |
description | We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats. |
format | Online Article Text |
id | pubmed-5925014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-59250142018-05-30 Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper Singh, Anshul Chaudhary, Ashu Bioinorg Chem Appl Research Article We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats. Hindawi 2018-04-12 /pmc/articles/PMC5925014/ /pubmed/29849539 http://dx.doi.org/10.1155/2018/2467463 Text en Copyright © 2018 Anshul Singh and Ashu Chaudhary. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Singh, Anshul Chaudhary, Ashu Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title_full | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title_fullStr | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title_full_unstemmed | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title_short | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
title_sort | synthesis, characterization, and biological evaluation of unimetallic and heterobimetallic complexes of bivalent copper |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925014/ https://www.ncbi.nlm.nih.gov/pubmed/29849539 http://dx.doi.org/10.1155/2018/2467463 |
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