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Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper

We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 mo...

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Autores principales: Singh, Anshul, Chaudhary, Ashu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925014/
https://www.ncbi.nlm.nih.gov/pubmed/29849539
http://dx.doi.org/10.1155/2018/2467463
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author Singh, Anshul
Chaudhary, Ashu
author_facet Singh, Anshul
Chaudhary, Ashu
author_sort Singh, Anshul
collection PubMed
description We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats.
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spelling pubmed-59250142018-05-30 Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper Singh, Anshul Chaudhary, Ashu Bioinorg Chem Appl Research Article We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl(2) and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats. Hindawi 2018-04-12 /pmc/articles/PMC5925014/ /pubmed/29849539 http://dx.doi.org/10.1155/2018/2467463 Text en Copyright © 2018 Anshul Singh and Ashu Chaudhary. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Singh, Anshul
Chaudhary, Ashu
Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title_full Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title_fullStr Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title_full_unstemmed Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title_short Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
title_sort synthesis, characterization, and biological evaluation of unimetallic and heterobimetallic complexes of bivalent copper
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925014/
https://www.ncbi.nlm.nih.gov/pubmed/29849539
http://dx.doi.org/10.1155/2018/2467463
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