Conventional DCs from Male and Female Lupus-Prone B6.NZM Sle1/Sle2/Sle3 Mice Express an IFN Signature and Have a Higher Immunometabolism That Are Enhanced by Estrogen

Type I interferons (IFN) are pathogenic in systemic lupus erythematosus (SLE) and were proposed to control the immunometabolism of dendritic cells (DCs). We previously reported that DCs from female lupus-prone mice constitutively overexpress IFN-responsive genes resembling the IFN signature found in...

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Detalles Bibliográficos
Autores principales: Lee, Michael H., Chakhtoura, Marita, Sriram, Uma, Caricchio, Roberto, Gallucci, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925037/
https://www.ncbi.nlm.nih.gov/pubmed/29850618
http://dx.doi.org/10.1155/2018/1601079

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