VDR Agonist Prevents Diabetic Endothelial Dysfunction through Inhibition of Prolyl Isomerase-1-Mediated Mitochondrial Oxidative Stress and Inflammation

BACKGROUND AND AIM: Upregulation of prolyl isomerase-1 (Pin1) protein expression and activity was associated with the pathogenesis of diabetic vasculopathy through induction of endothelial oxidative stress and inflammation. Moreover, VDR agonist protects against high glucose-induced endothelial apop...

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Detalles Bibliográficos
Autores principales: Zhang, Meijin, Lin, Liming, Xu, Changsheng, Chai, Dajun, Peng, Feng, Lin, Jinxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925189/
https://www.ncbi.nlm.nih.gov/pubmed/29849865
http://dx.doi.org/10.1155/2018/1714896

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