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Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis

Chuangxinmycin is an antibiotic isolated from Actinoplanes tsinanensis CPCC 200056 in the 1970s with a novel indole-dihydrothiopyran heterocyclic skeleton. Chuangxinmycin showed in vitro antibacterial activity and in vivo efficacy in mouse infection models as well as preliminary clinical trials. But...

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Detalles Bibliográficos
Autores principales:	Shi, Yuanyuan, Jiang, Zhibo, Li, Xingxing, Zuo, Lijie, Lei, Xuan, Yu, Liyan, Wu, Linzhuan, Jiang, Jiandong, Hong, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925218/ https://www.ncbi.nlm.nih.gov/pubmed/29719789 http://dx.doi.org/10.1016/j.apsb.2017.07.005

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