Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome

To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studie...

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Autores principales: Paixao, Enny S, Leong, Wei-Yee, Rodrigues, Laura C, Wilder-Smith, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925427/
https://www.ncbi.nlm.nih.gov/pubmed/29732381
http://dx.doi.org/10.1093/ofid/ofy073
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author Paixao, Enny S
Leong, Wei-Yee
Rodrigues, Laura C
Wilder-Smith, Annelies
author_facet Paixao, Enny S
Leong, Wei-Yee
Rodrigues, Laura C
Wilder-Smith, Annelies
author_sort Paixao, Enny S
collection PubMed
description To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes.
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spelling pubmed-59254272018-05-04 Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome Paixao, Enny S Leong, Wei-Yee Rodrigues, Laura C Wilder-Smith, Annelies Open Forum Infect Dis Brief Report To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes. Oxford University Press 2018-04-07 /pmc/articles/PMC5925427/ /pubmed/29732381 http://dx.doi.org/10.1093/ofid/ofy073 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Paixao, Enny S
Leong, Wei-Yee
Rodrigues, Laura C
Wilder-Smith, Annelies
Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title_full Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title_fullStr Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title_full_unstemmed Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title_short Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome
title_sort asymptomatic prenatal zika virus infection and congenital zika syndrome
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925427/
https://www.ncbi.nlm.nih.gov/pubmed/29732381
http://dx.doi.org/10.1093/ofid/ofy073
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