Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice

Alpha-synuclein (αSyn) is encoded by the first causal gene identified in Parkinson's disease (PD) and is the main component of Lewy bodies, a pathological hallmark of PD. aSyn-based animal models have contributed to our understanding of PD pathophysiology and to the development of therapeutics....

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Detalles Bibliográficos
Autores principales: Cai, Waijiao, Feng, Danielle, Schwarzschild, Michael A., McLean, Pamela J., Chen, Xiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925445/
https://www.ncbi.nlm.nih.gov/pubmed/29433982
http://dx.doi.org/10.1016/j.ebiom.2018.01.035

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