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IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

Chronic hepatitis leads to liver fibrosis and cirrhosis. Cirrhosis is a major cause of worldwide morbidity and mortality. Macrophages play a key role in fibrosis progression and reversal. However, the signals that determine fibrogenic vs fibrolytic macrophage function remain ill defined. We studied...

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Detalles Bibliográficos
Autores principales: Weng, Shih-Yen, Wang, Xiaoyu, Vijayan, Santosh, Tang, Yilang, Kim, Yong Ook, Padberg, Kornelius, Regen, Tommy, Molokanova, Olena, Chen, Tao, Bopp, Tobias, Schild, Hansjörg, Brombacher, Frank, Crosby, Jeff R., McCaleb, Michael L., Waisman, Ari, Bockamp, Ernesto, Schuppan, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925448/
https://www.ncbi.nlm.nih.gov/pubmed/29463471
http://dx.doi.org/10.1016/j.ebiom.2018.01.028