Anti-retroviral drugs: current state and development in the next decade

The pace of discovery of new antiretroviral (ARV) drugs has slowed, although the efficacy and safety of once-daily fixed dose combinations have been extensively investigated. Several traditional ARV drugs remain in phase III clinical trials. This review summarizes current information on ARV drugs in...

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Detalles Bibliográficos
Autor principal: Zhang, Xingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925449/
https://www.ncbi.nlm.nih.gov/pubmed/29719774
http://dx.doi.org/10.1016/j.apsb.2018.01.012
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author Zhang, Xingquan
author_facet Zhang, Xingquan
author_sort Zhang, Xingquan
collection PubMed
description The pace of discovery of new antiretroviral (ARV) drugs has slowed, although the efficacy and safety of once-daily fixed dose combinations have been extensively investigated. Several traditional ARV drugs remain in phase III clinical trials. This review summarizes current information on ARV drugs in phase III clinical trials and focuses on the development of ARV drugs in the next decade.
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spelling pubmed-59254492018-05-01 Anti-retroviral drugs: current state and development in the next decade Zhang, Xingquan Acta Pharm Sin B Review Article The pace of discovery of new antiretroviral (ARV) drugs has slowed, although the efficacy and safety of once-daily fixed dose combinations have been extensively investigated. Several traditional ARV drugs remain in phase III clinical trials. This review summarizes current information on ARV drugs in phase III clinical trials and focuses on the development of ARV drugs in the next decade. Elsevier 2018-03 2018-03-07 /pmc/articles/PMC5925449/ /pubmed/29719774 http://dx.doi.org/10.1016/j.apsb.2018.01.012 Text en © 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Zhang, Xingquan
Anti-retroviral drugs: current state and development in the next decade
title Anti-retroviral drugs: current state and development in the next decade
title_full Anti-retroviral drugs: current state and development in the next decade
title_fullStr Anti-retroviral drugs: current state and development in the next decade
title_full_unstemmed Anti-retroviral drugs: current state and development in the next decade
title_short Anti-retroviral drugs: current state and development in the next decade
title_sort anti-retroviral drugs: current state and development in the next decade
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925449/
https://www.ncbi.nlm.nih.gov/pubmed/29719774
http://dx.doi.org/10.1016/j.apsb.2018.01.012
work_keys_str_mv AT zhangxingquan antiretroviraldrugscurrentstateanddevelopmentinthenextdecade

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