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Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny

SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene...

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Detalles Bibliográficos
Autores principales: Cleary, Alan, Farmer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925771/
https://www.ncbi.nlm.nih.gov/pubmed/29194466
http://dx.doi.org/10.1093/bioinformatics/btx757
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author Cleary, Alan
Farmer, Andrew
author_facet Cleary, Alan
Farmer, Andrew
author_sort Cleary, Alan
collection PubMed
description SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene family memberships as a unit of search and comparison, the user interface enables quick and intuitive assessment of the degree of gene content divergence and the presence of various types of structural events within syntenic contexts. Insights into functionally significant differences seen at this level of abstraction can then serve to direct the user to more detailed explorations of the underlying data in other interconnected, provider-specific tools. AVAILABILITY AND IMPLEMENTATION: GCV is provided under the GNU General Public License version 3 (GPL-3.0). Source code is available at https://github.com/legumeinfo/lis_context_viewer. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-59257712018-05-04 Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny Cleary, Alan Farmer, Andrew Bioinformatics Applications Notes SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene family memberships as a unit of search and comparison, the user interface enables quick and intuitive assessment of the degree of gene content divergence and the presence of various types of structural events within syntenic contexts. Insights into functionally significant differences seen at this level of abstraction can then serve to direct the user to more detailed explorations of the underlying data in other interconnected, provider-specific tools. AVAILABILITY AND IMPLEMENTATION: GCV is provided under the GNU General Public License version 3 (GPL-3.0). Source code is available at https://github.com/legumeinfo/lis_context_viewer. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-11-29 2018-05-01 /pmc/articles/PMC5925771/ /pubmed/29194466 http://dx.doi.org/10.1093/bioinformatics/btx757 Text en © The Author(s) 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Cleary, Alan
Farmer, Andrew
Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title_full Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title_fullStr Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title_full_unstemmed Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title_short Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
title_sort genome context viewer: visual exploration of multiple annotated genomes using microsynteny
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925771/
https://www.ncbi.nlm.nih.gov/pubmed/29194466
http://dx.doi.org/10.1093/bioinformatics/btx757
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