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Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny
SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925771/ https://www.ncbi.nlm.nih.gov/pubmed/29194466 http://dx.doi.org/10.1093/bioinformatics/btx757 |
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author | Cleary, Alan Farmer, Andrew |
author_facet | Cleary, Alan Farmer, Andrew |
author_sort | Cleary, Alan |
collection | PubMed |
description | SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene family memberships as a unit of search and comparison, the user interface enables quick and intuitive assessment of the degree of gene content divergence and the presence of various types of structural events within syntenic contexts. Insights into functionally significant differences seen at this level of abstraction can then serve to direct the user to more detailed explorations of the underlying data in other interconnected, provider-specific tools. AVAILABILITY AND IMPLEMENTATION: GCV is provided under the GNU General Public License version 3 (GPL-3.0). Source code is available at https://github.com/legumeinfo/lis_context_viewer. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-5925771 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-59257712018-05-04 Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny Cleary, Alan Farmer, Andrew Bioinformatics Applications Notes SUMMARY: The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene family memberships as a unit of search and comparison, the user interface enables quick and intuitive assessment of the degree of gene content divergence and the presence of various types of structural events within syntenic contexts. Insights into functionally significant differences seen at this level of abstraction can then serve to direct the user to more detailed explorations of the underlying data in other interconnected, provider-specific tools. AVAILABILITY AND IMPLEMENTATION: GCV is provided under the GNU General Public License version 3 (GPL-3.0). Source code is available at https://github.com/legumeinfo/lis_context_viewer. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-11-29 2018-05-01 /pmc/articles/PMC5925771/ /pubmed/29194466 http://dx.doi.org/10.1093/bioinformatics/btx757 Text en © The Author(s) 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Cleary, Alan Farmer, Andrew Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title | Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title_full | Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title_fullStr | Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title_full_unstemmed | Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title_short | Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny |
title_sort | genome context viewer: visual exploration of multiple annotated genomes using microsynteny |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925771/ https://www.ncbi.nlm.nih.gov/pubmed/29194466 http://dx.doi.org/10.1093/bioinformatics/btx757 |
work_keys_str_mv | AT clearyalan genomecontextviewervisualexplorationofmultipleannotatedgenomesusingmicrosynteny AT farmerandrew genomecontextviewervisualexplorationofmultipleannotatedgenomesusingmicrosynteny |