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Enhancement of the catalytic activity of Isopentenyl diphosphate isomerase (IDI) from Saccharomyces cerevisiae through random and site-directed mutagenesis
BACKGROUND: Lycopene is a terpenoid pigment that has diverse applications in the food and medicine industries. A prospective approach for lycopene production is by metabolic engineering in microbial hosts, such as Escherichia coli. Isopentenyl diphosphate isomerase (IDI, E.C. 5.3.3.2) is one of the...
Autores principales: | Chen, Hailin, Li, Meijie, Liu, Changqing, Zhang, Haibo, Xian, Mo, Liu, Huizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925831/ https://www.ncbi.nlm.nih.gov/pubmed/29712558 http://dx.doi.org/10.1186/s12934-018-0913-z |
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